MicroRNA regulation via DNA methylation during the morula to blastocyst transition in mice†
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چکیده
منابع مشابه
MicroRNA regulation via DNA methylation during the morula to blastocyst transition in mice.
Epigenetic regulation is responsible for transcriptional silencing of genes and parental imprinting. This study addresses the question whether microRNAs (miRNAs) could be affected by DNA methylation during morula-blastocyst transition. Mouse embryos were treated with/without a DNA methyltransferase inhibitor (5-aza-2'-deoxycytidine, 5-aza-dC, 10 nM-5 μM). Changes of miRNAs were analyzed by quan...
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ژورنال
عنوان ژورنال: MHR: Basic science of reproductive medicine
سال: 2011
ISSN: 1460-2407,1360-9947
DOI: 10.1093/molehr/gar072